Influence of age, gender, and serum triglycerides on heart rate in a cohort of asymptomatic individuals without heart disease

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dc.contributor.authorRINALDO ARTES
dc.contributor.authorPaula, Rogério Silva de
dc.contributor.authorAntelmi, Ivana
dc.contributor.authorVincenzi, Marcos Antonio
dc.contributor.authorAndré, Carmen Diva Saldiva
dc.contributor.authorGrupi, Cesar José
dc.contributor.authorMansur, Alfredo José
dc.coverage.paisNão Informadopt_BR
dc.creatorPaula, Rogério Silva de
dc.creatorAntelmi, Ivana
dc.creatorVincenzi, Marcos Antonio
dc.creatorAndré, Carmen Diva Saldiva
dc.creatorGrupi, Cesar José
dc.creatorMansur, Alfredo José
dc.date.accessioned2022-08-17T00:29:52Z
dc.date.available2022-08-17T00:29:52Z
dc.date.issued2005
dc.description.notesTexto completopt_BR
dc.description.otherBackground: Age, sex and blood lipids were demonstrated in epidemiological studies to influence heart rate measured on physical examination, on 12-lead electrocardiogram or with automatic devices for short-term measurements. We hypothesized that in healthy individuals, age, sex and other clinical variables may also influence heart rate measured on 24-h ambulatory electrocardiographic monitoring. Methods: We studied 625 asymptomatic individuals with normal clinical examination, aged 15 to 83 (mean 42, standard deviation 11.9) years, 276 (44.2%) men and 349 (55.8%) women. Heart rate was evaluated on 24 h ambulatory electrocardiographic monitoring. Variables selected in univariate analysis (chi(2) and Student t tests) were further submitted to multivariate analysis with canonical correlation to assess the strength of associations between heart rate and other variables, and multiple linear regression models to generate reference curves. Results: Age was the most significant influence on canonical variable of heart rate relative to other clinical and laboratory variables (0.55; p<0.01). There was an increase in the minimum heart rate and a decrease of maximum heart rate with increasing age in both genders. The increase was steeper in men and the decrease was steeper in women. Minimum heart rate increased with increasing serum triglycerides and decreased as estimated maximum oxygen consumption increased. Conclusions: There was a narrower variation of heart rate with increasing age in both genders in healthy individuals. This variation was less pronounced in women. In addition, status of body haemostasis associated with peculiar metabolic conditions expressed in serum triglycerides levels may also be associated with heart rate.pt_BR
dc.format.extentp. 152-158pt_BR
dc.format.mediumDigitalpt_BR
dc.identifier.doihttps://doi.org/10.1016/j.ijcard.2004.11.023pt_BR
dc.identifier.issn1675273pt_BR
dc.identifier.issue2pt_BR
dc.identifier.urihttps://repositorio.insper.edu.br/handle/11224/4020
dc.identifier.volume105pt_BR
dc.language.isoInglêspt_BR
dc.publisherElsevier Ireland Ltdpt_BR
dc.relation.ispartofInternational Journal of Cardiologypt_BR
dc.rights.licenseO INSPER E ESTE REPOSITÓRIO NÃO DETÊM OS DIREITOS DE USO E REPRODUÇÃO DOS CONTEÚDOS AQUI REGISTRADOS. É RESPONSABILIDADE DOS USUÁRIOS INDIVIDUAIS VERIFICAR OS USOS PERMITIDOS NA FONTE ORIGINAL, RESPEITANDO-SE OS DIREITOS DE AUTOR OU EDITORpt_BR
dc.subject.keywordsHeart ratept_BR
dc.subject.keywordsAmbulatory electrocardiographic monitoringpt_BR
dc.subject.keywordsAmbulatory carept_BR
dc.subject.keywordsPreventive health servicept_BR
dc.titleInfluence of age, gender, and serum triglycerides on heart rate in a cohort of asymptomatic individuals without heart diseasept_BR
dc.typejournal article
dspace.entity.typePublication
local.subject.cnpqCiências Exatas e da Terrapt_BR
local.subject.cnpqCiências Humanaspt_BR
local.typeArtigo Científicopt_BR
relation.isAuthorOfPublication8b791c94-f3e5-4e04-af26-594195a8f576
relation.isAuthorOfPublication.latestForDiscovery8b791c94-f3e5-4e04-af26-594195a8f576
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