Wildfire-sourced fine particulate matter and preterm birth risks in Brazil: A nationwide population-based cohort study

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Autores

Zhang, Yiwen
Huang, Wenzhong
Xu, Rongbin
Ye, Tingting
Chen, Gongbo
Yue, Xu
Coêl , Micheline de Sousa Zanotti Stagliorio
Saldiva, Paulo Hilario Nascimento
Song, Jiangning
Guo, Yuming

Orientador

Co-orientadores

Citações na Scopus

Tipo de documento

Artigo Científico

Data

2024

Unidades Organizacionais

Centro de Pesquisa
Centro de Estudos das Cidades – Laboratório Arq.Futuro do Insper (Insper Cidades)
Resultado da parceria firmada entre Insper e Arq.Futuro em 2019, o Centro de Estudos das Cidades – Laboratório Arq.Futuro, que nasceu como Laboratório Arq.Futuro de Cidades do Insper e ganhou sua atual estrutura e a nova denominação em maio de 2024, tem na interdisciplinaridade a base de uma plataforma para o ensino e a pesquisa sobre o meio urbano, com foco na inovação.

Resumo

Wildfire-specific particulate matter with diameters ≤ 2.5 µm (PM2.5) is the key component of wildfire smoke, with potentially higher toxicity than PM2.5 from other sources. In this nationwide population-based cohort study, we included 22,163,195 births from Brazil during 2010–2019. Daily wildfire-specific PM2.5 was estimated through the chemical transport model. Time-varying Cox proportional hazards models were used to characterize the exposure-time-response (E-T-R) relationship between weekly wildfire-specific PM2.5 exposure and preterm birth (PTB) risks, followed by subgroup analyses. A 10 µg/m3 increment in wildfire-specific PM2.5 was associated with a hazard ratio of 1.047 (95 % confidence interval [CI]: 1.032–1.063) for PTB. Stronger associations between wildfire-specific PM2.5 and PTB were observed during earlier pregnancy, among female infants, and pregnant women < 18 years old, in ethnic minorities, with a length of education ≥ 11 years, from low-income or high temperature municipalities, and residing in North/Northeast regions. An estimated 1.47 % (95 % CI: 1.01 %–1.94 %) of PTBs were attributable to wildfire-specific PM2.5 in Brazil, increasing from 2010 to 2019. The PTBs attributable to wildfire-specific PM2.5 surpassed those attributed to non-wildfire PM2.5 (0.31 %, 95% CI: 0.09 %–0.57 %). Wildfire emerged as a critical source contributing to the PM2.5-linked PTBs. Prioritized fire management and emission control strategies are warranted for PTB prevention.

Palavras-chave

Cohort study; Wildfire-specific PM2.5; Preterm birth; Brazil; Critical exposure window; Time-varying Cox
Vínculo institucional

Titulo de periódico

Journal of Hazardous Materials
DOI

Título de Livro

URL na Scopus

Sinopse

Objetivos de aprendizagem

Idioma

Inglês

Notas

Membros da banca

Área do Conhecimento CNPQ

CIENCIAS DA SAUDE

CIENCIAS BIOLOGICAS::ECOLOGIA

CIENCIAS EXATAS E DA TERRA::GEOCIENCIAS

Citação

Avaliação

Revisão

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