Undifferentiated spondyloarthritis: a longterm followup

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dc.contributor.authorSampaio-Barros, Percival D.
dc.contributor.authorADRIANA BRUSCATO BORTOLUZZO
dc.contributor.authorConde, Roseneide A.
dc.contributor.authorCostallat, Adil M.
dc.contributor.authorBértolo, Samara
dc.contributor.authorBértolo, Manoel B.
dc.coverage.cidadeNão informadopt_BR
dc.coverage.paisNão Informadopt_BR
dc.creatorSampaio-Barros, Percival D.
dc.creatorConde, Roseneide A.
dc.creatorCostallat, Adil M.
dc.creatorBértolo, Samara
dc.creatorBértolo, Manoel B.
dc.date.accessioned2022-10-08T17:56:03Z
dc.date.available2022-10-08T17:56:03Z
dc.date.issued2010
dc.description.otherObjective. To analyze the longterm followup of a series of Brazilian patients with undifferentiated spondyloarthritis (uSpA). Methods. Prospective study analyzing a group of 111 patients with the diagnosis of uSpA, fulfilling the European Spondylarthropathy Study Group and the Amor criteria, who were followed for 5 to 10 years in a single university referral center. Patients had their outcome analyzed at 5, 7, and 10 years. Results. There was a predominance of men (81.1%), white ethnicity (78.4%), and positive HLA-B27 (61.3%), with a mean age at onset of 27.2 years. Twenty-seven patients presented development to ankylosing spondylitis (AS; 24.3%) and 3 to psoriatic arthritis (PsA; 2.7%), while 25 patients (22.5%) went into remission during the followup. Univariate logistic regression analysis revealed that ethnicity, HLA-B27, buttock pain, inflammatory low back pain, ankle involvement, grade I sacroiliitis at the beginning of the study, and the use of sulfasalazine were statistically associated with progression to AS. Multivariate logistic regression analysis revealed that HLA-B27 (p = 0.035, OR 6.720, 95% CI 11.45–39.43) and buttock pain (p = 0.009, OR 6.211, 95% CI 1.591–24.25) were statistically associated with progression to AS. Conclusion. In a longterm followup of 111 Brazilian patients with uSpA, HLA-B27 and buttock pain were significant predictors of progression to a definite disease. (J Rheumatol First Release May 1 2010; doi:10.3899/jrheum.090625)pt_BR
dc.format.extent5 p.pt_BR
dc.format.mediumDigitalpt_BR
dc.identifier.doi10.3899/jrheum.090625pt_BR
dc.identifier.urihttps://repositorio.insper.edu.br/handle/11224/4213
dc.language.isoInglêspt_BR
dc.publisherNão informadopt_BR
dc.relation.ispartofThe Journal of Rheumatologypt_BR
dc.rights.licenseO INSPER E ESTE REPOSITÓRIO NÃO DETÊM OS DIREITOS DE USO E REPRODUÇÃO DOS CONTEÚDOS AQUI REGISTRADOS. É RESPONSABILIDADE DOS USUÁRIOS INDIVIDUAIS VERIFICAR OS USOS PERMITIDOS NA FONTE ORIGINAL, RESPEITANDO-SE OS DIREITOS DE AUTOR OU EDITOR.pt_BR
dc.subject.keywordsUNDIFFERENTIATED SPONDYLOARTHRITHISpt_BR
dc.subject.keywordsOUTCOMEpt_BR
dc.subject.keywordsHLA-B27pt_BR
dc.subject.keywordsSACROILIITISpt_BR
dc.titleUndifferentiated spondyloarthritis: a longterm followuppt_BR
dc.typejournal article
dspace.entity.typePublication
local.identifier.sourceUrihttps://www.jrheum.org/content/early/2010/04/28/jrheum.090625
local.subject.cnpqCiências da Saúdept_BR
local.typeArtigo Científicopt_BR
relation.isAuthorOfPublicationccfd47d5-bd80-4464-98ce-629abb672e3d
relation.isAuthorOfPublication.latestForDiscoveryccfd47d5-bd80-4464-98ce-629abb672e3d
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