Social adjustment in depressed patients treated with venlafaxine and amitriptyline

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dc.contributor.authorRINALDO ARTES
dc.contributor.authorAndrade, Laura Helena Silveira Guerra
dc.contributor.authorGorenstein, Clarice
dc.contributor.authorMoreno, Ricardo Alberto
dc.coverage.cidadeLondrespt_BR
dc.coverage.paisReino Unidopt_BR
dc.creatorAndrade, Laura Helena Silveira Guerra
dc.creatorGorenstein, Clarice
dc.creatorMoreno, Ricardo Alberto
dc.date.accessioned2022-08-16T16:03:55Z
dc.date.available2022-08-16T16:03:55Z
dc.date.issued2002
dc.description.notesTexto completopt_BR
dc.description.otherSocial dysfunction is often associated with depressive disorders and its evaluation is an important measure of treatment outcome. The aim of this study was to assess the effect of two treatments, venlafaxine and amitriptyline, on the social functioning of depressed patients. Twenty-eight outpatients, meeting criteria for recurrent or single major depressive episodes, took part in a double-blind, 8-week trial with amitriptyline or venlafaxine (maximum of 150 mg/day) and were assessed by the Self-Report Social Adjustment Scale (SAS-SR) before and at the end of treatment. The scale was also applied to a carefully selected non-psychiatric sample. Both drugs showed the same efficacy on a clinical scale, but venlafaxine improved social functioning more than amitriptyline as only venlafaxine-treated patients reached SAS-SR values estimated for normal subjects. This effect might be linked to the higher rate of side-effects observed with amitriptyline.pt_BR
dc.format.extentp. 171-175pt_BR
dc.format.mediumDigitalpt_BR
dc.identifier.doihttp://dx.doi.org/10.1097/00004850-200207000-00003pt_BR
dc.identifier.issn14735857pt_BR
dc.identifier.issn02681315pt_BR
dc.identifier.issue4pt_BR
dc.identifier.urihttps://repositorio.insper.edu.br/handle/11224/4010
dc.identifier.volume17pt_BR
dc.language.isoInglêspt_BR
dc.publisherWolters Kluwer Health, Inc.pt_BR
dc.relation.ispartofInternational Clinical Psychopharmacologypt_BR
dc.rights.licenseO INSPER E ESTE REPOSITÓRIO NÃO DETÊM OS DIREITOS DE USO E REPRODUÇÃO DOS CONTEÚDOS AQUI REGISTRADOS. É RESPONSABILIDADE DOS USUÁRIOS INDIVIDUAIS VERIFICAR OS USOS PERMITIDOS NA FONTE ORIGINAL, RESPEITANDO-SE OS DIREITOS DE AUTOR OU EDITORpt_BR
dc.subject.keywordsantidepressantspt_BR
dc.subject.keywordsamitriptylinept_BR
dc.subject.keywordsdepressionpt_BR
dc.subject.keywordssocial adjusment scalept_BR
dc.subject.keywordssocial functioningpt_BR
dc.subject.keywordsvenlafaxinept_BR
dc.titleSocial adjustment in depressed patients treated with venlafaxine and amitriptylinept_BR
dc.typejournal article
dspace.entity.typePublication
local.subject.cnpqCiências Exatas e da Terrapt_BR
local.typeArtigo Científicopt_BR
relation.isAuthorOfPublication8b791c94-f3e5-4e04-af26-594195a8f576
relation.isAuthorOfPublication.latestForDiscovery8b791c94-f3e5-4e04-af26-594195a8f576

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