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4. Social adjustment in depressed patients treated with venlafaxine and amitriptyline

Type:	Artigo Científico
Title:	Social adjustment in depressed patients treated with venlafaxine and amitriptyline
Author:	Artes, Rinaldo Andrade, Laura Helena Silveira Guerra Gorenstein, Clarice Moreno, Ricardo Alberto
Publication Date:	2002
Abstract:	Social dysfunction is often associated with depressive disorders and its evaluation is an important measure of treatment outcome. The aim of this study was to assess the effect of two treatments, venlafaxine and amitriptyline, on the social functioning of depressed patients. Twenty-eight outpatients, meeting criteria for recurrent or single major depressive episodes, took part in a double-blind, 8-week trial with amitriptyline or venlafaxine (maximum of 150 mg/day) and were assessed by the Self-Report Social Adjustment Scale (SAS-SR) before and at the end of treatment. The scale was also applied to a carefully selected non-psychiatric sample. Both drugs showed the same efficacy on a clinical scale, but venlafaxine improved social functioning more than amitriptyline as only venlafaxine-treated patients reached SAS-SR values estimated for normal subjects. This effect might be linked to the higher rate of side-effects observed with amitriptyline.
Keywords (english terms):	antidepressants amitriptyline depression social adjusment scale social functioning venlafaxine
Language:	Inglês
CNPq Area:	Ciências Exatas e da Terra
Copyright:	O INSPER E ESTE REPOSITÓRIO NÃO DETÊM OS DIREITOS DE USO E REPRODUÇÃO DOS CONTEÚDOS AQUI REGISTRADOS. É RESPONSABILIDADE DOS USUÁRIOS INDIVIDUAIS VERIFICAR OS USOS PERMITIDOS NA FONTE ORIGINAL, RESPEITANDO-SE OS DIREITOS DE AUTOR OU EDITOR
Notes:	Texto completo
Appears in Collections:	Coleção de Artigos Científicos

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